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Blend words for domain names

Hi all

What does everyone thing about using blend words for domain names?

For instance.
Biopic - biography & picture
Glamping - Glomour & camping
Brightestar - Brightest & Star
Chillax - Chill & relax

Some of these are well known but what about using something like Brightestar.? Which isnt well know. Are there any disadvantages?

Many thanks to all in advance