Hi @Stan
To be specific this is when using https://video-url&autoplay=1 which is intended to play the video and bypass the restriction. It works fine with youtube and vimeo works in other browsers just not Chrome.
Also since I needed the video to play when a modal opened it is the desired behaviour as the user is clicking a play button on the page and then having to click play again on the video is not ideal UX. This also takes care of pausing the video when the user closes the modal.
I have updated my post to include some additional info, my solution unfortunately does not work with the Webflow Video element, so I added the iframe manually in an HTML embed.
With some more time I could maybe get it to work with the Webflow video element but based on the output when using this, Webflow adds a video iframe wrapper and then inside that iframe the video embed iframe is added. Therefore it needs javascript that will find the parent iframe and then inside that iframe find the vide iframe to trigger play and pause.